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Formestane Lentaron Powder
Formestane Lentaron Powder

Formestane Lentaron Powder

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

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Formestane


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


Anti Estrogen Medication Formestane CAS:566-48-3 For Treating Breast Cancer

Formestane Details:

Alias

Lentaron, 4-hydroxyandrost-4-ene-3,17-dione

CAS

566-48-3

Appearance

off-white crystalline powder

MF

C19H26O3

MW

302.41

Usage

An antitumor drug. An aromatase inhibitor

Dosage

250mg, 1 time every two weeks, as the arm deep intramuscular injection.

Density

1.19 g/cm3

Melting Point

199-202 ℃

Boiling Point

475.4 ℃ at 760 mmHg

Flash Point

255.4 ℃

Packing

Foil bag or as requirments

Grade

Pharmaceutical Grade


Description

Formestane (trade name Lentaron), also known as 4-hydroxyandrost-4-ene-3,17-dione, is a type I, steroidal, selective aromatase inhibitor.[1] It is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. The drug is not active orally, and is instead available only as an intramuscular depot injection. Because of this, it is no longer popular as many orally active aromatase inhibitors have been identified and introduced. Formestane is an analogue of androstenedione.

Formestane is often used to suppress the production of estrogens from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a weak aromatase inhibitor.

 

Formestane Application:

Formestane is a second generation, irreversible, steroidal aromatase inhibitor. It inhibits the aromatase enzyme responsible for converting androgens to estrogens, thereby preventing estrogen production. Breast cancer may be estrogen sensitive or insensitive. A majority of breast cancers are estrogen sensitive. Estrogen sensitive breast cancer cells depend on estrogen for viability.

Thus removal of estrogen from the body can be an effective treatment for hormone sensitive breast cancers. Formestane has been targeted specifically for the treatment of postmenopausal women. Unlike premenopausal women who produce most estrogen in the ovaries, postmenopausal women produce most estrogen in peripheral tissues with the help of the aromatase enzyme. Formestane, an aromatase inhibitor, can thus help to decrease the local production of estrogen by blocking the aromatase enzyme in peripheral tissues (ie. Adispose tissue of the breast) to treat hormone sensitive breast cancer.


Formestane COA

TEST ITEMS

SPECIFICATION

RESULTS

Description

: White or Almost White Crystalline Powder

white powder

Identification

: A.B.

Positive

Assay

: 97.0~103.0%

99.3%

Specific Rotation

: +101°~+105°

+102.6°

Loss On Drying

: 1.0%max

0.27%

Melting Point

: 153~157°C

153.0~155.0°C

Organic Volatile Impurities

: meets the requirement.

Conforms

Related Substances

: meets the requirement.

Conforms

Residual Solvents

: meets the requirement.

Conforms

Particle Size

: 100% ≤ 20 microns

Conforms

Conclusion

The specification conform with USP30 standard


Formestane Dosages

The most common version of formestane sold was in a topical gel form and it was dosed at 100-200mgs per application. Users would apply it onto clean, dry skin and rub in thoroughly; usually on the thighs or upper arms. It took 1 to 5 minutes to dry.

The injectable version for both breast cancer purposes and bodybuilders is 125mgs twice per week or 250mgs once per week.

 

Steroid hormone products:

Testosterone

58-22-0

Testosterone Enanthate

315-37-7

Testosterone Acetate

1045-69-8

Testosterone Propionate

57-85-2

Testosterone Cypionate

58-20-8

Testosaterone Decanoate

5721-91-5

Testosterone Undecanoate

5949-44-0

Testosterone Isocaproate

15262-86-9

Testosterone Phenylpropionate

1255-49-8

Methytestosterone

58-18-4

17a-Methyl-1-testosterone

65-04-3

Fluoxymesterone (Halotestin)

76-43-7

Mesterolone

1424-00-6

Sustanon 250


Boldenone

846-48-0

Boldenone Cypionate

106505-90-2

Boldenone Acetate

2363-59-9

Boldenone Undecylenate/Equipoise/EQ

13103-34-9

Metandienone(dianabol)

72-63-9

Methyltrienolone

965-93-5

Turinabol

2446-23-3

6-Bromoandrostenedione

38632-00-7

DHEA (Dehydroisoandrosterone)

53-43-0

Tibolone

5630-53-5

Oxymetholone/Anadrol

434-07-1

Stanolone

521-18-6

Stanozolol/Winstrol

10418-03-8

Methenolone Acetate(primonolan)

434-05-9

Methenolone Enanthate

303-42-4

Oxandrolone/Anavar

53-39-4

Nandrolone Decanoate

360-70-3

Nandrolone

434-22-0

Nandrolone Phenylpropionate

62-90-8

Trenbolone

10161-33-8

Trenbolone Enanthate

472-61-546

Trenbolone Acetate

10161-34-9

Trenbolone Hexahydrobenzyl Carbonate

23454-33-3

Drostanolone Enanthate

472-61-145

Drostanolone Propionate

521-12-0

Methasterone (Superdrol)

3381-88-2

Androstenedione

63-05-8

Dutasteride

164656-23-9

Dapoxetine Hydrochloride

129938-20-1

Sildenafil

139755-83-2

Avanafil

330784-47-9

Vardenafil

224785-90-4

Tadalafil

171596-29-5

Finasteride

98319-26-7

Letrozole

112809-51-5

Anastrozole (Arimidex)

120511-73-1

Salbutamol (albuterol)

51022-70-9

Dextromethorphan(DXM or DM)

125-71-3

Tamoxifen Citrate (nolvadex)

54965-24-1

roacuttane (Isotretinoin)

4759-48-2

Raloxifene Hydrochloride

82640-04-8

Yohimbine Hydrochloride

65-19-0

Clomifene Citrate (clomid)

50-41-9

Levothyroxine (L-thyroxine)(T4)

51-48-9

Liothyronine Sodium(T3)

6893-02-3

Trilostane

13647-35-3

Exemestane( Aromasin)

107868-30-4

Estrone

53-16-7

Estradiol

57-91-0

Estriol

50-27-1

Estradiol Benzoate

50-50-0

Estradiol enanthate

4956-37-0

19-norandrostenedione

734-32-7

Norethisterone Enanthate

3836-23-5

Megestrol acetate

595-33-5

Rimonabant

168273-06-1

Orlistat

96829-58-2

L-CARNITINE

541-15-1

Benzocaine

94-09-7

lidocaine hydrochloride

137-58-6

Tetracaine HCL

136-47-0


Our advantage:

1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;

2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;

3. Package: Professional packing with professional materials;

4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days;

5. Service: Best Service with after-sales service and consultation.


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