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Methylprednisolone Pharmaceutical Intermediates
Methylprednisolone Pharmaceutical Intermediates

Methylprednisolone Pharmaceutical Intermediates

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Methylprednisolone


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


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Name:

Methylprednisolone

CAS No.:

83-43-2

Formula:

C22H30O5

Molecular Weight:

374.52

EINECS:

201-476-4

Density:

1.28 g/cm3

Melting Point:

228-237 °C (dec.)

Boiling Point:

571.8 °C at 760 mmHg

Flash Point:

313.7 °C

Appearance:

White to off-white crystalline powder


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


Methylprednisolone Description

Methylprednisolone is a steroid that prevents the release of substances in the body that cause inflammation.

Methylprednisolone is used to treat many different inflammatory conditions such as arthritis, lupus, psoriasis, ulcerative colitis, allergic disorders, gland (endocrine) disorders, and conditions that affect the skin, eyes, lungs, stomach, nervous system, or blood cells.

Methylprednisolone may also be used for purposes not listed in this medication guide.

 

How should this medicine be used?

Methylprednisolone comes as a tablet to take by mouth. Your doctor will prescribe a dosing schedule that is best for you. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take methylprednisolone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not stop taking methylprednisolone without talking to your doctor. Stopping the drug abruptly can cause loss of appetite, upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. If you take large doses for a long time, your doctor probably will decrease your dose gradually to allow your body to adjust before stopping the drug completely. Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets. If these problems occur, call your doctor immediately. You may need to increase your dose of tablets temporarily or start taking them again.

 

Methylprednisolone COA

Items

Specifications

Results

Appearance

White to practically white crystalline powder

White crystalline powder

Melting

240°C

239°C

Identification

A:IR

Complies


B:UV

Complies


C: Positive reaction

Complies

Solubility

Practically insoluble in water sparingly soluble in alcohol, in dioxane, and in    methanol; slightly soluble in acetone and in chloroform; very slightly soluble in ether

Complies

Specific rotation

+79o~+86o

+82.7o

Loss on drying

≤1.0%

0.10%

Residue on ignition

≤0.2%

0.03%

Chromatographic purity

A: Individual impurity ≤1.0%

0.40%


B: Total impurities≤2.0%

1.10%

Assay

97.0~103.0%

99.80%

Conclusion

The results conforms to the USP34



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