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Estradiol Benzoatae Pharmaceutical Intermediates
Estradiol Benzoatae Pharmaceutical Intermediates

Estradiol Benzoatae Pharmaceutical Intermediates

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

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Estradiol Benzoatae


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


Product Name

Estradiol Benzoate

Synonyms

beta-Estradiol-3-benzoate; Oestradiol Benzoate; 17beta-Estradiol benzoate; 1,3,5(10)-Estratriene-3,17b-diol    3-benzoate; 3,17b-Dihydroxy-1,3,5(10)-estratriene 3-benzoate; (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;

Molecular Formula

C25H28O3

Molecular Weight

376.488

InChI

InChI=1/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1

CAS Registry Number

50-50-0

EINECS

200-043-7

Molecular Structure


Density

1.185g/cm3

Melting point

191-198C

Boiling point

531.2°C at 760 mmHg

Refractive index

1.604

Flash point

212C

Vapour Pressure

4.08E-12mmHg at 25C

Assay

99%

Appearance

White or light yellow crystalline powder



The menstrual cycle in women involves predictable variations in the levels of several hormones, with estradiol being one of them. It is involved in the ovulation process and prepares the inner lining of the uterus for implantation, should the egg be fertilized. Certain tests done on baboons and other primates have indicated that his hormone also plays a continual role in maintaining a pregnancy, helping it to last for the full gestation period.

 

Application
The effects of daily injections of 5 microgram estradiol benzoate (EB) on the patterns of food and ethanol consumption were studied in ovarectomized rats given free access to food, a 10% ethanol solution, and water. EB led to an immediate, but transient, suppression of both food and ethanol intake. The time course and magnitude of these effects were virtually identical.
While the decrease in total food intake was achieved by a permanent decrease in the duration of eating bouts, the decline in total ethanol consumption apparently resulted from decreased rates of licking within bouts. Gradual increases in the frequency of eating and ethanol-drinking bouts allowed total food and ethanol intake to return to baseline within three weeks of the first injection.

Total water intake rose three-fold during EB administration and this was due to increases in both the duration and frequency of drinking bouts. The similarity in effects induced by EB on the patterns of food and ethanol intake were discussed in terms of ethanol's caloric property.

 

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1.Rich experience. Our company is a professional production leading factory in China for many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East and so many other countries , and we have got very good feedback from our customers, we had Established long friendly relations of cooperation.

2.Great quality, purity and favorable price. Good quality is one of our secret success!

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