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Dextromethorphan Hydrobromide Pharmaceutical Intermediates
Dextromethorphan Hydrobromide Pharmaceutical Intermediates

Dextromethorphan Hydrobromide Pharmaceutical Intermediates

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

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Dextromethorphan Hydrobromide


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


Abstract

Dextromethorphan Hydrobromide is the hydrobromide salt form of dextromethorphan, a synthetic, addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
Dextromethorphan Hydrobromide (DXM or DM) is an antitussive (cough suppressant) drug of the morphinan class with sedative and dissociative properties. It is one of the active ingredients in many over-the-counter cold and cough medicines, including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, and others. Dextromethorphan has also found numerous other uses in medicine, ranging from pain relief (as either the primary analgesic, or an opioid potentiater) over psychological applications to the treatment of addiction. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.


Specification

Product Name

Dextromethorphan Hydrobromide

Synonyms

Dextromethorphan maleate HBR; dextromethorphan HBR;
(9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan    hydrobromide; 3-methoxy-17-methylmorphinan hydrobromide;
(9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide hydrate;
Destromethorphan hydrobromide

Molecular Formula

C18H28BrNO2

Molecular Weight

370.3244

InChI

InChI=1/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1

CAS Registry Number

125-69-9

EINECS

204-750-1

Boiling point

486.1C at 760 mmHg

Flash point

247.8 C

Vapour Pressure

2.92E-10mmHg at 25 C

Assay

99%

Appearance

White or white crystalline powder

Application

DXM is also used recreationally.When exceeding label-specified maximum dosages,dextromethorphan acts as a dissociative hallucinogen.Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.

The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic such as and .As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.


Use

1.For dry cough,including upper respiratory tract infection (such as cold,pharyngitis,bronchitis,cough).

2.Research reagents,widely used in molecular biology,pharmacology research.This is the central antitussive,can inhibit the medulla cough centrum antitussive effect and produce.The antitussive effect is equal to or slightly.The general treatment dose not inhibit respiration,long-term use of no addiction and tolerance.

 

Steroid Use
To the steroid user, the incorporation of TUDCA into any cycle regimen is key to help guard your body
from bad side-effects. Over time, someone who has been using a moderate amount of oral steroids can
put a serious strain on their liver. As the steroids pass through the liver and metabolize, they cause cell
damage. The damage to liver cells by steroids can lead to jaundice and serious liver disease. In addition,
steroids can directly inhibit the production and flow of bile from the liver, this is known as cholestasis.
TUDCA has been used to help the bile flow (fix cholestasis) and help cleanse out the liver.
TUDCA isn't just for use during steroid cycles. It should also be used in post cycle therapy (PCT). When
you run a steroid cycle, your heart and liver are sure to become strained. Continuing to cleanse your
body during post-cycle therapy, when you are off the steroids, can help you release the built up toxins.
This should help you feel better and return to your health levels before the cycle started. Those that blast
and cruise (BnC) can also take advantage of TUDCA, as it cleanses the liver rather effectively even
during BnC runs . In simple terms, it means more blasting and less cruising.

Other Benefits
Studies have shown that TUDCA also helps with blood glucose and insulin.another study showed it aided
fat loss and helped neutralize weight in both men and women. So in other words, if you are overweight it
will aid in weight loss and if you are underweight it can help you gain some lean mass.


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Peptides

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CJC-1295DAC 863288-34-0

(2mg/vial)

PT-141 32780-32-8

(10mg/vial)

Melanotan-II

(10mg/vial)

GHRP-6 87616-84-0

(5mg/vial)

Hexarelin 140703-51-1

(2mg/vial)

Oxytocin

(2mg/vial)

pentadecapeptide BPC 157

(2mg/vial)

Triptorelin Acetate

(2mg/vial)

Tesamorelin 106612-94-6

(2mg/vial)

Selank

(5mg/vial)

Carbetocin Acetate 37025-55-1

(1G / foil bag)

EGF 62253-63-8

(1KG / fluorinated bottle)

Thymosin 1 Acetate 62304-98-7

(1G / polypeptide tube)

PEG-MGF

(2mg/vial)

CJC-1295

(2mg/vial)

Melanotan-I

(10mg/vial)

GHRP-2 158861-67-7

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Ipamorelin 170851-70-4

(2mg/vial)

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(1G / foil bag)

Desmopressin acetate 16789-98-3

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