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Follistatin 315 Myostatin Blockers
Follistatin 315 Myostatin Blockers

Follistatin 315 Myostatin Blockers

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

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  • Product Details

Follistatin 315


1mg/Vial White Solid Peptides Follistatin 315 For Muscle Growth

 

Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


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Basic Infor----------Follistatin 315


Product Name

 

Follistatin 315

 

Specification

 

1mg/vial

Purity

 

98%min

 

Appearance

 

White powder

Specific Optical Rotation (c=0.5,10% HAc)

-50.0~-60.0°

 

Water Content(Karl Fischer)

 

≤5.0%

Acetate Content(by HPLC)

 

≤15.0%

Amino Acid Composition

 

±10% of theoretical

 

Purity (by HPLC)

 

≥98.0%

Single Impurity(by HPLC)

 

≤1.0%

Peptide Content(by %N)

 

≥80%

Assay(By Anhydrous, Acetic Acid-free )

 

95.0~105.0%

Bacterial Endotoxins

 

≤5EU/mg

Storage/Stability

 

Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended

Usage

 

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining  porcine (re: pig) follicular fluid in the ovaries.



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Follistatin 315 Description

 

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.

The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA.

 

Follistatin is a secreted glycoprotein that was first identified as a folliclestimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGF like and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.

 

Follistatin 315 Applications

 

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.

 

Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it.

Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

 

Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.

 

Follistatin and Muscle Growth

Follistatin works by binding to and inhibiting transforming growth factor- (TGF-) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.

 

In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function. However, FSH levels that are too low can also negatively impact health and reproductive capabilities.

 

 


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